Search on: CASPASE 12 
Descriptors Found: 1
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Descriptor English:   Caspase 12 
Descriptor Spanish:   Caspasa 12 
Descriptor Portuguese:   Caspase 12 
Tree Number:   D08.811.277.656.262.500.126.550.920
D08.811.277.656.300.200.126.550.920
D12.644.360.075.405.550.920
D12.776.476.075.405.550.920
Definition English:   A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES. 
History Note English:   2007(2000) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52230 
Unique Identifier:   D053454 

Occurrence in VHL:
 

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